If you're into workflow runners, Reflow and Cromwell (https://github.com/broadinstitute/cromwell https://github.com/broadinstitute/cromwell) are the only two re

If you're into workflow runners, Reflow and Cromwell (https://github.com/broadinstitute/cromwell https://github.com/broadinstitute/cromwell) are the only two really to consider. Having tried them all, these two are by far the best and most supported (and there are 100s!) Cromwell is great because it is google cloud native and supported within the Terra ecosystem (https://app.terra.bio/ https://app.terra.bio/) meaning you do not need to host it yourself - you can just connect your google account and go. Reflow, I've heard, is a little more "professional" given that the Grail team is heavily ex-Google. But both can scale to massively parallel (1000+ parallel analyses).