4 ms·
Pretty interesting. Incidentally, I discovered that I actually have a balanced whole arm translocation of chromosomes 5 and 16. That is I have one normal 5, on
by 2mur 15y ago
Pretty interesting.
Incidentally, I discovered that I actually have a balanced whole arm translocation of chromosomes 5 and 16. That is I have one normal 5, one normal 16, and two abnormal chromosomes one with a 5p/16q and one with a 5q/16p. I only found it out when I rotated through a cytogenetics lab and we dropped our own chromosomes for grins. It's not a Robertsonian translocation (doesn't involved acrocentric chromosomes) but it's right through the centromeres of 5 and 16. Pretty weird, but as far as I can tell, totally asymptomatic. I'm a physician (and hobby-python guy) and have 4 completely normal kids.
- th0ma5 15y agoThank you for posting this for the perspective, and it seems like this kind of random curiosity could be a nice mundane reminder of the random beauty of life, but one never knows and perhaps someone will find a genetic variance someday that is really curious and leads to something great!
- tocomment 15y agoWait so how could you have Children?
- blahedo 15y agoHe has a normal 5 and a normal 16 as well as the modified versions.
- beambot 15y agoMy guess... The usual way. ;-) He can still pass on the normal 5 & 16.
- 2mur 15y agoYeah my oldest kid was slow to talk (fine now) so his pediatrician wanted to make sure there wasn't anything wrong, so his chromosomes were done (as well as Fragile X and all the other usual suspects). The report came back as normal chromosomes, so I can only assume he got my normal 5 and 16 (or that my wife was stepping out!!).
- spottiness 15y agoDid your wife ever have a miscarriage? If not, I would guess it's very likely (>90%) that sperms with the chromosomes with the translocation can't fertilize an egg.
- tocomment 15y agoHow does genetic recombination during meosis work with a setup like that?