For rare occassions where a numpad is desired you could use a dedicated one. There is even an IPv6 calculator numpad. Which also works great for MAC addresses.

For rare occassions where a numpad is desired you could use a dedicated one. There is even an IPv6 calculator numpad. Which also works great for MAC addresses. There is no reason why you cannot have specific keybinds or maps for such a purpose though, except muscle memory / learning curve.