Do you think it might be possible to appreciate the reality and sincerity of someone's experiences while also questioning the validity of their interpretations?

Do you think it might be possible to appreciate the reality and sincerity of someone's experiences while also questioning the validity of their interpretations? Would this be a form of substantive engagement on the merits of the piece? Personally, I see someone describing a number of points of cultural difference and an author who wholeheartedly believes they have identified the root of all of them. Is it worth discussing that the real, indisputably valid lived experience of the author, might also be linked to other things?