3 ms·
my point was: in this case we know this is an unproven mechanism; because we are designing a drug that makes use of a mechanism. But we're using empirically di
by ithkuil 5y ago
my point was: in this case we know this is an unproven mechanism; because we are designing a drug that makes use of a mechanism.
But we're using empirically discovered drugs since forever, where we had no idea on how the thing even supposed to act, let alone the consequence of this action.
- avereveard 5y agoEmpirical drugs also came from an age where the alternative was cutting the part that hurt and hoping for the best. You have to do better than the alternatives, and it was easier at a time when alternatives had 60% mortality. That said, this could be a good alternative than straight up dying for those in critical conditions. It would however tell us nothing about its safety, as people in critical condition have some deal of damage taken by the coronavirus itself and it'll be hard to control for each secondary effects.