If you prefer in video form: https://youtu.be/byFEU1A5MRY https://youtu.be/byFEU1A5MRY If you're short on time jump to this slide: https://www.youtube.com/wa

If you prefer in video form: https://youtu.be/byFEU1A5MRY https://youtu.be/byFEU1A5MRY If you're short on time jump to this slide: https://www.youtube.com/watch?v=byFEU1A5MRY&t=1583s https://www.youtube.com/watch?v=byFEU1A5MRY&t=1583s What the WHO did to the Ivermectin evidence base? * Single person served as Chair of Guidance Support, & member of Methods Committee, and Systematic Review Team * Failed to publish a pre-established protocol for data exclusion * Excluded trials.. that were included in their original Unitaid search protocol * Excluded two "quasi-randomized" RCT's finding statistically significant lower mortality * Excluded two RCT's compared to/given with other medications, finding statistically significant lower mortality * Excluded up to seven or more other available Ivermectin RCT results * Excluded all RCT's and OCT's investigating Ivermectin in the prevention of COVID-19 * Excluded 13 OCT's with over 5,500 patients, overall large reductions in mortality found * Excluded numerous published and pre-print epidemiologic studies finding population wide mortality decreases * Included only 3 studies such that this limited dataset allowed them to "suggest" increased harms of Ivermectin * Graded the JAMA study as "low risk of bias" yet all independent expert reviewers have graded as high risk of bias * Downgraded the quality of evidence on mortality due to "imprecision" despite displaying a precise estimate