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> For what it's (not) worth, it prompted me to sign up today. :) More for my understanding than anything else, and with every guarantee that I won't present a

> For what it's (not) worth, it prompted me to sign up today. :) More for my understanding than anything else, and with every guarantee that I won't present any follow-up questions or statements, but why was this the tipping point and not the actual disease risk mitigation resulting from the vaccine?

tbihl 5y ago
Not me, but a coworker of mine is the only guy in my office who hasn't been vaccinated (rest of us got second dose at end of January) because of adverse reactions to past (milder) vaccinations. He correctly assesses that he's in a very low risk environment, but at some point he'll probably risk the vaccine to not have pariah status. But for the last 3 months, there was nothing to make the tradeoff worthwhile to him.
- hnra 5y ago
  Glad that he didn’t value not being a disease vector which could spread the virus to someone who may be at risk. Vaccines work when most of society get vaccinated, it only requires a small minority of egos to make a forgotten disease rear its ugly head again.
josephcsible 5y ago
My guess: GP is young and healthy, so the chance of significant harm from COVID is nearly zero, and the vaccines for COVID have significantly worse side effects than pretty much any other vaccines given today. Thus, until today, it was a high-risk low-reward proposition.
- lamontcg 5y ago
  The risk and severity of bad effects from COVID exceed the risks and severity of the bad effects from the vaccine across all age categories. It is a low-risk, higher-reward proposition for everyone. And even if all the virus does is fry your sense of smell you're better off with a few days of influenza-like symptoms from the vaccines.
  - josephcsible 5y ago
    You can't just weigh "The risk and severity of bad effects from COVID" with "the risks and severity of the bad effects from the vaccine". You also need to factor in that the probability of an unvaccinated person getting COVID isn't 100%.
    - scythe 5y ago
      About 10-30% of Americans got COVID-19 so far, depending on how you tally the numbers. Of those, approximately 8% can be expected to experience long-term effects that disrupt their daily lives: https://www.medpagetoday.com/infectiousdisease/covid19/91270 https://www.medpagetoday.com/infectiousdisease/covid19/91270 >About 8% of all participants said at least one activity of daily living suffered long-term consequences, most commonly household chores. That puts the net risk for non-vaccinated people at no less than 0.8%. By contrast, the incidence of blood clots from the AstraZeneca vaccine, which caused its ouster, was about 0.001%. That's a factor of 800 in favor of vaccination with the worst of the vaccines.
      - josephcsible 5y ago
        Those numbers don't factor in age or preexisting conditions at all.
        scythe 5y ago
        The safety factor is 800. Preexisting conditions and age aren't going to change the conclusion.
      - tryonenow 5y ago
        And how do you measure the mid to long term risk of a novel mRNA technology which is effectively in trial now, under emergency approval, when vaccines typically take years of safety evaluations? Particularly considering that there are preprints out with a mechanism identified for reverse transcription of the spike producing mRNA, which could result in chronic inflammatory disease in some proportion of recipients, given that other preprints claim that the spike protein itself is a general inflammatory agent and may be responsible for clotting/vascular symptoms. Note that reverse transcription of COVID RNA also is a convenient explanation for post symptomatic positive tests as well as long COVID symptoms. I think it's irresponsible to downplay the risks associated with this novel technology, especially when people still have the option of continuing to socially isolate to some degree.
- nielsbot 5y ago
  Newer variants are hitting young people harder. COVID is getting more dangerous to that group. Plus, as other posters have said, the vaccine is extremely safe.
- interviewer0000 5y ago
  More or less spot on, but add a whole boat load of laziness to the equation.
postalrat 5y ago
It was the first clear sign that the CDC is confident in the vaccine.
interviewer0000 5y ago
Bleh, i'm 25, healthy, and more than all, lazy. But if it means I can take my mask off and be honest. I'm down.
- eganist 5y ago
  Thanks, and thanks for getting it. :)

tbihl 5y ago

Not me, but a coworker of mine is the only guy in my office who hasn't been vaccinated (rest of us got second dose at end of January) because of adverse reactions to past (milder) vaccinations. He correctly assesses that he's in a very low risk environment, but at some point he'll probably risk the vaccine to not have pariah status. But for the last 3 months, there was nothing to make the tradeoff worthwhile to him.

hnra 5y ago
Glad that he didn’t value not being a disease vector which could spread the virus to someone who may be at risk. Vaccines work when most of society get vaccinated, it only requires a small minority of egos to make a forgotten disease rear its ugly head again.

josephcsible 5y ago

My guess: GP is young and healthy, so the chance of significant harm from COVID is nearly zero, and the vaccines for COVID have significantly worse side effects than pretty much any other vaccines given today. Thus, until today, it was a high-risk low-reward proposition.

lamontcg 5y ago
The risk and severity of bad effects from COVID exceed the risks and severity of the bad effects from the vaccine across all age categories. It is a low-risk, higher-reward proposition for everyone. And even if all the virus does is fry your sense of smell you're better off with a few days of influenza-like symptoms from the vaccines.
- josephcsible 5y ago
  You can't just weigh "The risk and severity of bad effects from COVID" with "the risks and severity of the bad effects from the vaccine". You also need to factor in that the probability of an unvaccinated person getting COVID isn't 100%.
  - scythe 5y ago
    About 10-30% of Americans got COVID-19 so far, depending on how you tally the numbers. Of those, approximately 8% can be expected to experience long-term effects that disrupt their daily lives: https://www.medpagetoday.com/infectiousdisease/covid19/91270 https://www.medpagetoday.com/infectiousdisease/covid19/91270 >About 8% of all participants said at least one activity of daily living suffered long-term consequences, most commonly household chores. That puts the net risk for non-vaccinated people at no less than 0.8%. By contrast, the incidence of blood clots from the AstraZeneca vaccine, which caused its ouster, was about 0.001%. That's a factor of 800 in favor of vaccination with the worst of the vaccines.
    - josephcsible 5y ago
      Those numbers don't factor in age or preexisting conditions at all.
      - scythe 5y ago
        The safety factor is 800. Preexisting conditions and age aren't going to change the conclusion.
    - tryonenow 5y ago
      And how do you measure the mid to long term risk of a novel mRNA technology which is effectively in trial now, under emergency approval, when vaccines typically take years of safety evaluations? Particularly considering that there are preprints out with a mechanism identified for reverse transcription of the spike producing mRNA, which could result in chronic inflammatory disease in some proportion of recipients, given that other preprints claim that the spike protein itself is a general inflammatory agent and may be responsible for clotting/vascular symptoms. Note that reverse transcription of COVID RNA also is a convenient explanation for post symptomatic positive tests as well as long COVID symptoms. I think it's irresponsible to downplay the risks associated with this novel technology, especially when people still have the option of continuing to socially isolate to some degree.
nielsbot 5y ago
Newer variants are hitting young people harder. COVID is getting more dangerous to that group. Plus, as other posters have said, the vaccine is extremely safe.
interviewer0000 5y ago
More or less spot on, but add a whole boat load of laziness to the equation.

postalrat 5y ago

It was the first clear sign that the CDC is confident in the vaccine.

interviewer0000 5y ago

Bleh, i'm 25, healthy, and more than all, lazy. But if it means I can take my mask off and be honest. I'm down.

eganist 5y ago
Thanks, and thanks for getting it. :)