In my experience no - at least on current iterations - for very specific things such as a text editor where the DOM isn't really prepared to deal with the way i

In my experience no - at least on current iterations - for very specific things such as a text editor where the DOM isn't really prepared to deal with the way it (the editor) has to be structured probably yes, if you knew what you're doing - but for most things not really - and to have the same functionality you would need to implement a lot of things by yourself (even if functionally it would work it wouldn't have the same accessibility unless you did that yourself and not sure how much you can fully emulate it).