4 ms·
High NAbs titers in the blood against spike will almost certainly be protective and even in the absence of sterilizing mucosal immunity will confine any infecti
by lamontcg 6y ago
High NAbs titers in the blood against spike will almost certainly be protective and even in the absence of sterilizing mucosal immunity will confine any infection to the upper respiratory tract.
I'm nowhere near as concerned about a variant infecting my upper respiratory tract as I am with being unvaccinated and having any of the variants attack my heart, kidneys, lungs and blood.
The use of spike was also not a mistake. Attempts to produce vaccines against NP for SARS-CoV-1 produced signs of ADE, so that is why everyone is using spike-only (other than the few inactivated virus vaccines).