I would say nothing, except maybe for how many mentions it gets in HW-review articles. Unless you are in numerical HPC or kernel programming, you do not need t

I would say nothing, except maybe for how many mentions it gets in HW-review articles. Unless you are in numerical HPC or kernel programming, you do not need to think about NUMA, but it is not black/white, it is a slope. Varnish tries to do certain things "NUMA-friendly", without actually being "NUMA-aware" as such, and the kernels seem to do a really good job with that.