If they are a CEO and they do that just before a big investment meeting to the point that everyone notices something is wrong and someone else has to take over

If they are a CEO and they do that just before a big investment meeting to the point that everyone notices something is wrong and someone else has to take over the lead. All of that when you know your current investors are trying to reduce the risk of the company. You'd probably be in trouble. And if on top if that you would be freely talking to the press about various issues even after the board has asked you to stop it. You'd be fired. Which is exactly what happened here. If your company is big enough to think going public, "Let's try LSD just before a big meeting" is not exactly the kind of idea you want your CEO to have.