It works alright with React if you treat it like regular DOM elements, but there's rough edges like SSR event handlers not working: https://github.com/facebook/

It works alright with React if you treat it like regular DOM elements, but there's rough edges like SSR event handlers not working: https://github.com/facebook/react/issues/18390 https://github.com/facebook/react/issues/18390 Unfortunately it seems facebook isn't prioritizing fixing issues like this. I'd suggest using preact if you want a framework that's more compatible with web components but gives you the React experience.