Huge fan of eBPF but admittedly less informed than I could be; could someone point out some instances where this wouldn't be able to replace agent instrumentati

Huge fan of eBPF but admittedly less informed than I could be; could someone point out some instances where this wouldn't be able to replace agent instrumentation eventually? I understand the bits of the kernel we're able to hook this way are still being built out, but 5yrs down the road what would we still need other instrumentation to capture?