I think a big part of it is how genuinely fucked up the US healthcare system is. This sows a lot of distrust towards all related industries, including the pharm

I think a big part of it is how genuinely fucked up the US healthcare system is. This sows a lot of distrust towards all related industries, including the pharmaceutical industry. Not at all saying this is a true or justified belief, but from what I can gather many of the skeptics think this is a scam designed to profit Big Pharma. Others are equally disposed to distrust government in general. And on top of that you had a president who politicized the pandemic from the very beginning, meaning for many people there is simply no way for them to view the situation rationally or objectively.