3 ms·
It seems like with HIV they can simply sequence the prevalent evolutionary outcome in your body within a month and give your body the blueprint to destroy that
by vmception 6y ago
It seems like with HIV they can simply sequence the prevalent evolutionary outcome in your body within a month and give your body the blueprint to destroy that version
What typically happens with HIV is that the body kills most of it initially, but the remaining ones keep rapidly evolving until an iteration evades your immune response, this takes about 12 years. Seems like an mRNA vaccine could be done every 3 years for individuals and either completely eradicate the HIV presence in the body or do it once every 12 years for a reset
Let me know if I fundamentally misunderstand something
- robbiep 6y agoThat's not quite true - HIV of course mutates but in-patient mutations are generally considered to have a negligible effect on outcomes/have a negligible effect as a driver of morbidity . What is the big driver of HIV is in the name, it's a Immunodeficiency virus - it kills CD4+ T cells and other cells of the immune system. At a certain point you don't have enough CD4+ T cells left and you lose your adaptive/cell-mediated immune system and then you're in big trouble. Essentially it's a war of attrition and unless you're part of some tiny proportion of people who have either a form of immunity against it or an immune system that for whatever reason is able to continue waging war on it then you will succumb