4 ms·

Interestingly, they saw the same pathway patterns in non-coffee drinkers upon drinking coffee. I wonder whether the effect isn’t particularly “hardwired”, but i

• graderjs 6y ago
  Right, but if you look at Fig 1 the center of mass are higher for NCD pos than CD, so there's a definite trend but it's not the same. What makes this stronger is that CD had no coffee for 3 hours prior to the start of the study (and because the study began with interview, and ended with MRI, and was roughly 3 hours long, CD could have been off coffee for around 6 hours). So in CD I think the difference can only be accounted for by pathway changes, not bloodstream caffeine, meaning it is hardwired for habitual CD. But it is interesting that they see the same network traces occurring in NCD given coffee. It would be cool to see how long it took NCD pos to go back to baseline.