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Weren’t the first viral vector vaccines (for Ebola virus) only recently approved? As to track record, the first viral vector vaccines in widespread use (i.e. t
by ummonk 6y ago
Weren’t the first viral vector vaccines (for Ebola virus) only recently approved?
As to track record, the first viral vector vaccines in widespread use (i.e. the COVID vaccines) will have killed hundreds (possibly even thousands) of people via blood clots. That’s a worthwhile trade off for a disease as deadly as COVID. But it would be less acceptable against less dangerous diseases, particularly if safer vaccine technologies are available.
- gus_massa 6y agoThe MMR vaccine contains "live" weakened virus. The kid sometimes get some small red points in the skin that disappear in a few days. The oral polio vaccine "Sabin" has "live" virus. It's stronger than the injectable polio vaccine, but there is a small risk that the virus can escape and mutate and after a year or so cause polio to another person. So countries without polio cases, only use the injectable version "Salk" that does not contain "live" virus. The first smallpox vaccine was just a similar virus for cows. The latest smallpox vaccine also used a "live" virus.
- meepmorp 6y agoNone of those are VVVs, though.