5 ms·

If it works, not very well. There were some very small underpowered studies that showed promise. Then large RCTs were done and it didn’t work. Brazil would cert

If it works, not very well. There were some very small underpowered studies that showed promise. Then large RCTs were done and it didn’t work. Brazil would certainly not be in the situation it’s in right now if ivermectin cured covid. https://www.gavi.org/vaccineswork/ivermectin-why-potential-covid-treatment-isnt-recommended-use https://www.gavi.org/vaccineswork/ivermectin-why-potential-c...

herenow2021 5y ago
No, all the trials show benefit. One RCT trial published in Jama, even despite severe flaws such as giving ivermectin in the placebo group, still showed benefit. The conflict of interests with that study are large though, so a significant number of independent doctors have written a letter describing the flaws in the study and why it should be retracted: https://jamaletter.com/ https://jamaletter.com/ The situation with Brazil is that Ivermectin has become politicized, so that it is not widely used in the country. When you compare cities that use it versus cities that don't the results are striking: https://covid19criticalcare.com/ivermectin-in-covid-19/epidemiologic-analyses-on-covid19-and-ivermectin/ https://covid19criticalcare.com/ivermectin-in-covid-19/epide...
- Lhd 5y ago
  Interesting and very frustrating that these kinds of studies and analysis do not reach any decision-making outcomes. Unfortunately not only Ivermectin became politicized, but the whole Brazilian health situation. For example, 4 health ministers since the beginning of the pandemic (a military general amongst them) and an early investment in hydroxychloroquine without solid scientific proofs (while at the same time refusing to buy Pfizer vaccines).
- drcongo 5y ago
  It's weird how often on threads about covid, an entirely new HN account turns up to defend the other newly created account that is extolling the virtues of Ivermectin.

herenow2021 5y ago

No, all the trials show benefit. One RCT trial published in Jama, even despite severe flaws such as giving ivermectin in the placebo group, still showed benefit. The conflict of interests with that study are large though, so a significant number of independent doctors have written a letter describing the flaws in the study and why it should be retracted: https://jamaletter.com/ https://jamaletter.com/ The situation with Brazil is that Ivermectin has become politicized, so that it is not widely used in the country. When you compare cities that use it versus cities that don't the results are striking: https://covid19criticalcare.com/ivermectin-in-covid-19/epidemiologic-analyses-on-covid19-and-ivermectin/ https://covid19criticalcare.com/ivermectin-in-covid-19/epide...

Lhd 5y ago
Interesting and very frustrating that these kinds of studies and analysis do not reach any decision-making outcomes. Unfortunately not only Ivermectin became politicized, but the whole Brazilian health situation. For example, 4 health ministers since the beginning of the pandemic (a military general amongst them) and an early investment in hydroxychloroquine without solid scientific proofs (while at the same time refusing to buy Pfizer vaccines).
drcongo 5y ago
It's weird how often on threads about covid, an entirely new HN account turns up to defend the other newly created account that is extolling the virtues of Ivermectin.