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Awesome! They should totally go all out investigating this. The rest of us should totally not get too excited. Many drugs go into phase 1. Few come out. Th
by rossdavidh 6y ago
Awesome! They should totally go all out investigating this.
The rest of us should totally not get too excited. Many drugs go into phase 1. Few come out. There are more phases after that. Tamiflu got through all of that and still hasn't been a game-changer for something that kills tens of thousands in the U.S.A. alone every year.
But, hey, you have to take a lot of shots on goal before you get one, so I'm glad they're going after it with a sense of urgency.
- symlinkk 6y agoWhich phases did the vaccine go through?
- rossdavidh 6y agoNot sure why the downvotes, it's a legitimate question. So there's a phase to see if there are huge side-effects in humans, then a phase to see what dosage to use for effectiveness, then a larger (tens of thousands) phase to get enough data to justify using it on millions of people. I think there are normally more phases after that when you're not in a pandemic.
- sp332 6y agoWhich vaccine?
- epgui 6y agoThey all went through at least phase III, even Russia's Sputnik vaccine (even though they announced it as a success before they had their phase III completed).
- ascorbic 6y agoThe Merck/Pasteur vaccine was abandoned after stage 1. The Sanofi vaccine had poor stage 1 results, but they seem to be indicating that they plan to continue development with a much later projected laucnh date. I don't know if that is because they mean they're trying a different candidate entirely or if they're making changes to the failed one.
- epgui 6y agoWell, yes, my assumption was that he was asking about the vaccines that are currently in use. The fraction of drugs/treatments, broadly speaking, that make it past stage 3, is <1%.