So, I'm not sure about vaccines, but I can say something about insulin. Lantus' patent expired, and then Basaglar came in. It's the same insulin, apart from som

So, I'm not sure about vaccines, but I can say something about insulin. Lantus' patent expired, and then Basaglar came in. It's the same insulin, apart from some inactive ingredients (which just dilute it, afaik), and the fabrication process[1]. But 1 unit of lantus and 1 unit of basaglar contains the exact same amount of the same insulin formula. Basaglar costs less, some many people are changing to it. And still, a lot of people had trouble adjusting, and even those that adjusted, some report that for a few days, their glucose levels were high and not coming down. Some had to adjust the daily dose to be slightly higher. I'm not sure if that same problem would happen for mRNA vaccines, but it's important to keep in mind that the whole manufacturing process + quality control can make a difference. [1] https://www.goodrx.com/blog/lantus-vs-basaglar-effectiveness-dosing-side-effects-cost/ https://www.goodrx.com/blog/lantus-vs-basaglar-effectiveness...