https://www.nature.com/articles/s41398-019-0604-5 https://www.nature.com/articles/s41398-019-0604-5 Those studies reported higher coffee drinkers had 31–65% de

https://www.nature.com/articles/s41398-019-0604-5 https://www.nature.com/articles/s41398-019-0604-5 Those studies reported higher coffee drinkers had 31–65% decrease in the risk of AD dementia, which is quite comparable to about 65% decrease of Aβ positivity rate in higher coffee drinkers (27.14%) compared to lower coffee drinkers (17.61%). Furthermore, the relationship between higher coffee intake and lower Aβ positivity was prominent for lifetime coffee intake than for current coffee intake. This suggests that the protective effects of higher coffee intake against Aβ pathology involve the chronic effects associated with prolonged exposure rather than an acute or short-term effect. Note: "coffee drinkers" not "caffeine"