3 ms·

The average risk of thrombosis the J&J and AstraZeneca vaccine have are between 1 in 100,000 to 1 in 250,000. To put some perspective, estrogen-based medication

by m-p-3 6y ago

The average risk of thrombosis the J&J and AstraZeneca vaccine have are between 1 in 100,000 to 1 in 250,000. To put some perspective, estrogen-based medication like the contraceptive pill have a risk of 1 in 1,000.

mikem170 6y ago
Careful, You might be comparing apples and oranges... Contraceptive pill blood clot risk is for any type of blood clot, such as deep vein thrombosis, pulmonary embolism, etc [0]. The vaccine cerebral venous sinus thrombosis blood clot risk is something like 1 in 100k+ (as you mentioned), but during J&J FDA trials of 20k people there were 50% more blood clots of other various types in the vaccinated group [1] (15 blood clots in vaccinated group versus 10 in the placebo group, which the FDA did not consider statistically significant at the time) You may be comparing fatal-only vaccine blood clots to non-fatal contraception blood clots, and ignoring non-fatal vaccine blood clots. I'm not saying this to throw the vaccine under the bus, just pointing out that the comparison of the odds you presented might not be fair. [0] https://thefemedic.com/contraception/blood-clots-thrombosis-combined-contraceptive-pill/ https://thefemedic.com/contraception/blood-clots-thrombosis-... [1] https://www.cnn.com/2021/04/13/health/johnson-vaccine-blood-clots-cdc-fda/index.html https://www.cnn.com/2021/04/13/health/johnson-vaccine-blood-...
- mlyle 6y ago
  > You may be comparing fatal-only vaccine blood clots to non-fatal contraception blood clots At the time vaccination was paused, here were 6 known cases of CVST, 2 fatal, in 6.8 million vaccinated. To come up with 1 in 250,000 like the OP, you need to consider only women (~3.5 million doses), count all cases (not just the fatalities), and assume more than half of the cases were not reported.

3 ms·

The average risk of thrombosis the J&J and AstraZeneca vaccine have are between 1 in 100,000 to 1 in 250,000. To put some perspective, estrogen-based medication

by m-p-3 6y ago

mikem170 6y ago
Careful, You might be comparing apples and oranges... Contraceptive pill blood clot risk is for any type of blood clot, such as deep vein thrombosis, pulmonary embolism, etc [0]. The vaccine cerebral venous sinus thrombosis blood clot risk is something like 1 in 100k+ (as you mentioned), but during J&J FDA trials of 20k people there were 50% more blood clots of other various types in the vaccinated group [1] (15 blood clots in vaccinated group versus 10 in the placebo group, which the FDA did not consider statistically significant at the time) You may be comparing fatal-only vaccine blood clots to non-fatal contraception blood clots, and ignoring non-fatal vaccine blood clots. I'm not saying this to throw the vaccine under the bus, just pointing out that the comparison of the odds you presented might not be fair. [0] https://thefemedic.com/contraception/blood-clots-thrombosis-combined-contraceptive-pill/ https://thefemedic.com/contraception/blood-clots-thrombosis-... [1] https://www.cnn.com/2021/04/13/health/johnson-vaccine-blood-clots-cdc-fda/index.html https://www.cnn.com/2021/04/13/health/johnson-vaccine-blood-...
- mlyle 6y ago
  > You may be comparing fatal-only vaccine blood clots to non-fatal contraception blood clots At the time vaccination was paused, here were 6 known cases of CVST, 2 fatal, in 6.8 million vaccinated. To come up with 1 in 250,000 like the OP, you need to consider only women (~3.5 million doses), count all cases (not just the fatalities), and assume more than half of the cases were not reported.