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It seems that this boils down to nicotine intake vs no nicotine intake. I wonder if this protective effect would change for people who use other tobacco product

by jdhn 6y ago

It seems that this boils down to nicotine intake vs no nicotine intake. I wonder if this protective effect would change for people who use other tobacco products, such as dip or snus.

moistbar 6y ago
I'd be even more curious to see if it holds true for people who vape, since vape juice tends to have very little in it besides nicotine, polyethylene glycol, and flavoring.
- grawprog 6y ago
  I wonder if the form of nicotine would make a difference. Many brands of cigarettes use a tobacco that's been 'enhanced' with freebase nicotine to increase addictiveness among other things but others do not and the amount of freebase nicotine varies wildly between brands. https://www.newscientist.com/article/dn3990-crack-nicotine-in-cigarettes-varies-widely/ https://www.newscientist.com/article/dn3990-crack-nicotine-i... and vape juice comes in both freebase form and salt form. https://www.ruthlessvapor.com/blogs/ruthless-e-liquid/nicotine-salt-vs-freebase-why-nicotine-salt-is-the-new-craze https://www.ruthlessvapor.com/blogs/ruthless-e-liquid/nicoti... Nicotine in a freebase form is absorbed more quickly into our bodies and in higher concentrations that nicotine in salt form.
  - Rastonbury 6y ago
    For vaping, those with nic salts are way more concentrated (used in Juul)
    - grawprog 6y ago
      Yes, they're more concentrated because in salt form our brains don't absorb as much of it. Like the difference between doing a bump of coke and a hit of crack. You gotta do a lot of coke to get the same high.
- King-Aaron 6y ago
  Or to expand on that, nicotine gum or nasal sprays
deleted 6y ago
[deleted]
pomian 6y ago
Or is it more about smoking? That could mean that standing around a campfire is better for you, in regards to COVID. The article mentions nitric oxide. Smoking also reduces the amount of oxygen inhaled by anyone smoking. Perhaps COVID needs clean air, or oxygen rich air. Conversely, I thought one of the theories for Italy experiencing high problems(mortality) with COVID, was the preponderance is smokers. Then again, there were reports last year, of air pollution as contributor to severity. It will be interesting to see what we learn five years from, when we have been able to look at more complete data sets.

by jdhn 6y ago

It seems that this boils down to nicotine intake vs no nicotine intake. I wonder if this protective effect would change for people who use other tobacco products, such as dip or snus.

moistbar 6y ago

I'd be even more curious to see if it holds true for people who vape, since vape juice tends to have very little in it besides nicotine, polyethylene glycol, and flavoring.

grawprog 6y ago
I wonder if the form of nicotine would make a difference. Many brands of cigarettes use a tobacco that's been 'enhanced' with freebase nicotine to increase addictiveness among other things but others do not and the amount of freebase nicotine varies wildly between brands. https://www.newscientist.com/article/dn3990-crack-nicotine-in-cigarettes-varies-widely/ https://www.newscientist.com/article/dn3990-crack-nicotine-i... and vape juice comes in both freebase form and salt form. https://www.ruthlessvapor.com/blogs/ruthless-e-liquid/nicotine-salt-vs-freebase-why-nicotine-salt-is-the-new-craze https://www.ruthlessvapor.com/blogs/ruthless-e-liquid/nicoti... Nicotine in a freebase form is absorbed more quickly into our bodies and in higher concentrations that nicotine in salt form.
- Rastonbury 6y ago
  For vaping, those with nic salts are way more concentrated (used in Juul)
  - grawprog 6y ago
    Yes, they're more concentrated because in salt form our brains don't absorb as much of it. Like the difference between doing a bump of coke and a hit of crack. You gotta do a lot of coke to get the same high.
King-Aaron 6y ago
Or to expand on that, nicotine gum or nasal sprays

deleted 6y ago

[deleted]

pomian 6y ago

Or is it more about smoking? That could mean that standing around a campfire is better for you, in regards to COVID. The article mentions nitric oxide. Smoking also reduces the amount of oxygen inhaled by anyone smoking. Perhaps COVID needs clean air, or oxygen rich air. Conversely, I thought one of the theories for Italy experiencing high problems(mortality) with COVID, was the preponderance is smokers. Then again, there were reports last year, of air pollution as contributor to severity. It will be interesting to see what we learn five years from, when we have been able to look at more complete data sets.