Yes and no. "Take the red pill" comes from the Matrix, but the adjective "redpilled" is associated with a particular political and ideological fringe which star

Yes and no. "Take the red pill" comes from the Matrix, but the adjective "redpilled" is associated with a particular political and ideological fringe which started on Reddit's /r/TheRedPill, from which descended the various incel subreddits, MGTOW, etc. - to be fair, it wasn't that negative initially, just a bit questionable, but as it happens these days the place became more and more politicised, radical, hating women, and associated with the American far right and emotionally stunted angry teenagers.