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>I think also the instability is a large component of why the vaccines must be stored at such low temperatures. As I understand it, the low temperatures are par
by wolfi1 6y ago
>I think also the instability is a large component of why the vaccines must be stored at such low temperatures.
As I understand it, the low temperatures are partly required because of the liposomes the mRNA is "packed" into
- danwills 6y agoAs I understand the instability of mRNA in the general cell background cytoplasm is because of the presence of enzymatic molecules (produced by the cell) that attract and then break down (lyse) any mRNA that floats into their 'jaws'. Loads of different things get broken-down by this kind of background presence of some enzyme, and since mRNA is used by the cell itself, maybe not too surprising that it has a cleanup mechanism in-place already?
- danwills 6y agoCommented at the wrong level sorry!, I didn't respond to what parent post was saying, meant to extend elsewhere...