3 ms·
So, is it because prions managed to attain a lower energy configuration than similar proteins, forcing them to reconfigure themselves upon contact with a prion,
by bitL 6y ago
So, is it because prions managed to attain a lower energy configuration than similar proteins, forcing them to reconfigure themselves upon contact with a prion, causing a cascade of protein deformation that is super stable and can't be reversed? Like protein configuration = local minimum, prion configuration = global minimum?
- trenchgun 6y agoIt's like the protein version of vacuum collapse.