Not when you use language like, "I've kissed four guys in the past year." If I had to try to nail down when it is and isn't inclusive, I would say that when it

Not when you use language like, "I've kissed four guys in the past year." If I had to try to nail down when it is and isn't inclusive, I would say that when it is used in the second-person, where a speaker is directly addressing a group, it is the most likely to be gender-neutral: "Do you guys like this idea? Can I get you guys anything?" When it is used in a first- or third-person perspective, it's less likely to be used in a gender-neutral way. "I know some guys who work there" tends to be used only if you're talking about men. If you're talking about women only or a mixed group, it's more common to say, "I know some women who work there" or "I know some people who work there."