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.. Covid19 designer drugs.. . Druggable pocket in the SARS-CoV-2 spike protein: https://news.ycombinator.com/item?id=24567458 https://news.ycombinator.com/ite
by thro1 6y ago
.. Covid19 designer drugs..
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Druggable pocket in the SARS-CoV-2 spike protein: https://news.ycombinator.com/item?id=24567458 https://news.ycombinator.com/item?id=24567458, https://www.youtube.com/watch?v=EMaKFcpV5wg https://www.youtube.com/watch?v=EMaKFcpV5wg
https://www.sciencemediacentre.org/expert-reaction-to-study- https://www.sciencemediacentre.org/expert-reaction-to-study-...
The linoleic acid-binding pocket in SARS-COV-2 will make an attractive target for possible designer drugs..
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hrsACE2 as well inhibits binding: https://news.ycombinator.com/item?id=25008048 https://news.ycombinator.com/item?id=25008048 , https://www.youtube.com/watch?v=EMaKFcpV5wg https://www.youtube.com/watch?v=EMaKFcpV5wg
APN001 is a hrsACE2 designed by Apeiron Biologics to imitate the human enzyme ACE2.
hrsACE2 at tissue sites can effectively compete with the endogenous ACE2 and limits SARS-CoV-2 entrance into the host cells
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