5 ms·

After my second jab I honestly don’t care. Time to get on with life. We have someone in our family that can’t be vaccinated for medical reasons and they feel t

After my second jab I honestly don’t care. Time to get on with life. We have someone in our family that can’t be vaccinated for medical reasons and they feel the same way. The risk goes down significantly when the whole family is vaccinated. It’s time to put covid in the “managed risk” section of our life and get on with things.

jghn 6y ago
Yep. I'll feel bad for the people who can't get a jab due to lack of herd immunity and I'll worry about the anti-vaxxers leading to escape. But even with that I know I won't be able to help but have a "screw 'em" stance pretty quick with the people who are choosing to not get vaccinated.
barbazoo 6y ago
Given that it seems that you can be transmitting the virus without developing symptoms, would it really be that much safer for an unvaccinated person?
- jghn 6y ago
  Depends on your vaccine. NEJM had a RWE study on Pfizer from Israel's data [1] that showed the 2nd shot had 92% efficacy against asymptomatic infection. Symptomatic infection was 94%. [1]: https://www.nejm.org/doi/full/10.1056/NEJMoa2101765 https://www.nejm.org/doi/full/10.1056/NEJMoa2101765
  - barbazoo 6y ago
    That's fantastic, thank you.
idiotsecant 6y ago
You should care because your vaccine doesn't necessarily prevent you from catching a mutated variant . Given a long enough timeline and enough hosts such a strain will evolve, it's only a matter of time.
- mikem170 6y ago
  Is there any science supporting your statement?
  - idiotsecant 6y ago
    You want a source for what? That viruses are subject to evolutionary pressures and will mutate to better adapt to their environments like literally everything else as advantageous random mutations are found?
    - mikem170 6y ago
      You seem to be overstating the likelihood of covid-19 mutating into another strain, like the flu does. It's a coronavirus and those are known to be different in this regard. I haven't seen a source saying that we should expect immunity-evading strains. Do you have anything decent?
      - idiotsecant 6y ago
        They literally already exist!
        mikem170 6y ago
        >You should care because your vaccine doesn't necessarily prevent you from catching a mutated variant . Given a long enough timeline and enough hosts such a strain will evolve, it's only a matter of time. Yes, I know there are variants. But I've seen no science saying that it is likely or expected that the vaccine won't work against covid-19 variants. Have you? > They literally already exist! Ok, I googled and found this: "Variant or strain? Experts explain what's happened to the coronavirus" [0] From the article: "However, Soucy noted that all currently known variants of COVID-19 belong to the SARS-CoV-2 strain and have not mutated enough to either be classified as their own strain or be ineffective against current and prospective COVID-19 vaccines." Another quote from the article: "Infectious disease expert Dr. Lisa Barrett told CTV News Channel on Sunday that viruses often mutate, but some viruses do it more than others. She noted that while the genetic code of coronaviruses does typically change over time, she says the mutations aren’t normally a cause for concern." Here's another article, with references to multiple studies: "We now have the best evidence yet that everyone develops long-term coronavirus immunity after infection — and it's not just about antibodies" [1] From that article: "Many people who've never gotten COVID-19 seem to have memory T cells that can recognize the new coronavirus." ... "In this case, experts think these cross-reactive T cells likely come from previous exposure to other coronaviruses — those that cause common colds." That's the kind of stuff I find when I dig into this. What are you seeing? [0] https://www.ctvnews.ca/health/coronavirus/variant-or-strain-experts-explain-what-s-happened-to-the-coronavirus-1.5245923 https://www.ctvnews.ca/health/coronavirus/variant-or-strain-... [1] https://www.businessinsider.com/long-term-coronavirus-immunity-t-cells-2020-8?op=1 https://www.businessinsider.com/long-term-coronavirus-immuni...

jghn 6y ago

Yep. I'll feel bad for the people who can't get a jab due to lack of herd immunity and I'll worry about the anti-vaxxers leading to escape. But even with that I know I won't be able to help but have a "screw 'em" stance pretty quick with the people who are choosing to not get vaccinated.

barbazoo 6y ago

Given that it seems that you can be transmitting the virus without developing symptoms, would it really be that much safer for an unvaccinated person?

jghn 6y ago
Depends on your vaccine. NEJM had a RWE study on Pfizer from Israel's data [1] that showed the 2nd shot had 92% efficacy against asymptomatic infection. Symptomatic infection was 94%. [1]: https://www.nejm.org/doi/full/10.1056/NEJMoa2101765 https://www.nejm.org/doi/full/10.1056/NEJMoa2101765
- barbazoo 6y ago
  That's fantastic, thank you.

idiotsecant 6y ago

You should care because your vaccine doesn't necessarily prevent you from catching a mutated variant . Given a long enough timeline and enough hosts such a strain will evolve, it's only a matter of time.

mikem170 6y ago
Is there any science supporting your statement?
- idiotsecant 6y ago
  You want a source for what? That viruses are subject to evolutionary pressures and will mutate to better adapt to their environments like literally everything else as advantageous random mutations are found?
  - mikem170 6y ago
    You seem to be overstating the likelihood of covid-19 mutating into another strain, like the flu does. It's a coronavirus and those are known to be different in this regard. I haven't seen a source saying that we should expect immunity-evading strains. Do you have anything decent?
    - idiotsecant 6y ago
      They literally already exist!
      - mikem170 6y ago
        >You should care because your vaccine doesn't necessarily prevent you from catching a mutated variant . Given a long enough timeline and enough hosts such a strain will evolve, it's only a matter of time. Yes, I know there are variants. But I've seen no science saying that it is likely or expected that the vaccine won't work against covid-19 variants. Have you? > They literally already exist! Ok, I googled and found this: "Variant or strain? Experts explain what's happened to the coronavirus" [0] From the article: "However, Soucy noted that all currently known variants of COVID-19 belong to the SARS-CoV-2 strain and have not mutated enough to either be classified as their own strain or be ineffective against current and prospective COVID-19 vaccines." Another quote from the article: "Infectious disease expert Dr. Lisa Barrett told CTV News Channel on Sunday that viruses often mutate, but some viruses do it more than others. She noted that while the genetic code of coronaviruses does typically change over time, she says the mutations aren’t normally a cause for concern." Here's another article, with references to multiple studies: "We now have the best evidence yet that everyone develops long-term coronavirus immunity after infection — and it's not just about antibodies" [1] From that article: "Many people who've never gotten COVID-19 seem to have memory T cells that can recognize the new coronavirus." ... "In this case, experts think these cross-reactive T cells likely come from previous exposure to other coronaviruses — those that cause common colds." That's the kind of stuff I find when I dig into this. What are you seeing? [0] https://www.ctvnews.ca/health/coronavirus/variant-or-strain-experts-explain-what-s-happened-to-the-coronavirus-1.5245923 https://www.ctvnews.ca/health/coronavirus/variant-or-strain-... [1] https://www.businessinsider.com/long-term-coronavirus-immunity-t-cells-2020-8?op=1 https://www.businessinsider.com/long-term-coronavirus-immuni...