3 ms·

Related: https://news.ycombinator.com/item?id=26842629 https://news.ycombinator.com/item?id=26842629 .

• thro1 6y ago
  .. Covid19 designer drugs.. . Druggable pocket in the SARS-CoV-2 spike protein: https://news.ycombinator.com/item?id=24567458 https://news.ycombinator.com/item?id=24567458, https://www.youtube.com/watch?v=EMaKFcpV5wg https://www.youtube.com/watch?v=EMaKFcpV5wg https://www.sciencemediacentre.org/expert-reaction-to-study- https://www.sciencemediacentre.org/expert-reaction-to-study-... The linoleic acid-binding pocket in SARS-COV-2 will make an attractive target for possible designer drugs.. . hrsACE2 as well inhibits binding: https://news.ycombinator.com/item?id=25008048 https://news.ycombinator.com/item?id=25008048 , https://www.youtube.com/watch?v=EMaKFcpV5wg https://www.youtube.com/watch?v=EMaKFcpV5wg APN001 is a hrsACE2 designed by Apeiron Biologics to imitate the human enzyme ACE2. hrsACE2 at tissue sites can effectively compete with the endogenous ACE2 and limits SARS-CoV-2 entrance into the host cells . ?