3 ms·

25 is as they say 'medium-to-heavy dose'. It's not as excessively high as you make it sound and it isn't quite 'an white knuckle, ego-obliterating flight throug

by Tenoke 6y ago

25 is as they say 'medium-to-heavy dose'. It's not as excessively high as you make it sound and it isn't quite 'an white knuckle, ego-obliterating flight through space' It's definitely a 'proper trip' but you are making it seem like a DMT breakthrough amount.

mtalantikite 6y ago
Yeah, agreed. I know mushrooms are highly variable in their psilocybin and psilocin content, but it’s generally around 1% of dried mass for cubensis from what I’ve read. So in this case that’s what, 2.5 grams of mushrooms about? That’s not nothing, but it certainly isn’t an ego death sort of dose. I know a lot of people that will take 3.5 grams for a typical “journey” when they’re seeking to get in there and do some internal work. It seems like a perfectly fine dose for a study like this: not too overwhelming and not too small.
- rank0 6y ago
  I guess we can agree to disagree. You can absolutely experience ego death in this range (or at least 'ego-shaking'). An 1/8th is pretty normal yeah for the typical recreational user, but I don't think that's a great benchmark for a science experiment. Lots of people have scary unpleasant experiences with an 1/8 or less. Pharmaceutical grade psilocybin is gonna be a lot more potent than average street mushrooms.
rank0 6y ago
Everyone has different bodies and react differently to drugs. I can assure you that 25mg is a heavy dose especially for those who are not experienced with psychedelics. My whole point is that some of these tests are being administered by scientists who have no experience with the drug, and maybe they should be more careful. I would use different language to describe a DMT trip, but the imagery wasn't supposed to be the main focus of my comment. Just for an additional reference check out this old study and its take on dosage: https://erowid.org/references/texts/show/5665docid5442 https://erowid.org/references/texts/show/5665docid5442 administered 20-70mg but eventually settled on "30 mg. as a standard, moderate dose". But'moderate' may mean many things. Leary, later in the same paper, says "Psilocybin produces temporary states of spiritual conversion, interpersonal closeness and psychological insight. Forty-five percent of the entire inmate group clearly underwent a mystical, transcendent, death-rebirth experience."

by Tenoke 6y ago

mtalantikite 6y ago

Yeah, agreed. I know mushrooms are highly variable in their psilocybin and psilocin content, but it’s generally around 1% of dried mass for cubensis from what I’ve read. So in this case that’s what, 2.5 grams of mushrooms about? That’s not nothing, but it certainly isn’t an ego death sort of dose. I know a lot of people that will take 3.5 grams for a typical “journey” when they’re seeking to get in there and do some internal work. It seems like a perfectly fine dose for a study like this: not too overwhelming and not too small.

rank0 6y ago
I guess we can agree to disagree. You can absolutely experience ego death in this range (or at least 'ego-shaking'). An 1/8th is pretty normal yeah for the typical recreational user, but I don't think that's a great benchmark for a science experiment. Lots of people have scary unpleasant experiences with an 1/8 or less. Pharmaceutical grade psilocybin is gonna be a lot more potent than average street mushrooms.

rank0 6y ago

Everyone has different bodies and react differently to drugs. I can assure you that 25mg is a heavy dose especially for those who are not experienced with psychedelics. My whole point is that some of these tests are being administered by scientists who have no experience with the drug, and maybe they should be more careful. I would use different language to describe a DMT trip, but the imagery wasn't supposed to be the main focus of my comment. Just for an additional reference check out this old study and its take on dosage: https://erowid.org/references/texts/show/5665docid5442 https://erowid.org/references/texts/show/5665docid5442 administered 20-70mg but eventually settled on "30 mg. as a standard, moderate dose". But'moderate' may mean many things. Leary, later in the same paper, says "Psilocybin produces temporary states of spiritual conversion, interpersonal closeness and psychological insight. Forty-five percent of the entire inmate group clearly underwent a mystical, transcendent, death-rebirth experience."