4 ms·

There’s a Twitter feed dedicated to this caveat https://mobile.twitter.com/justsaysinmice?lang=en https://mobile.twitter.com/justsaysinmice?lang=en

• mjfl 6y ago
  For diseases where the causal mechanism is known very well, mouse models aren't that bad: Rett syndrome, hemophilia, spinal muscular atrophy. It gets to be a problem where the disease is poorly defined and the cause is unknown: Alzheimers, schizophrenia, ADHD, etc. It is very important that people have this discrimination power and not jump to "All of this is bad" or "All of this is good".
  • ghodith 6y ago
    Also in a lot of cases it’s the best we’ve got. You might be able to use monkeys but even that doesn’t change a lot of the problems. If you move from animal models you aren’t going to suddenly be able to start experimenting on humans.
  • bumby 6y ago
    Very good point. I always considered that Twitter profile as tongue-in-cheek, rather than being outright dismissive.