3 ms·
“Reduce APOE” is an oversimplified view. The mechanisms by which the AD-associated E4 genotype (arg112, arg158) results in disease are still poorly understood.
by benrapscallion 6y ago
“Reduce APOE” is an oversimplified view. The mechanisms by which the AD-associated E4 genotype (arg112, arg158) results in disease are still poorly understood. The main therapeutic hypothesis for AD is to reduce the levels of pathogenic plaques and aggregates using antibodies.
- kick_in_the_doo 6y agoInteresting. And these studies have shown that medicine which reduces these plaques doesn't actually help with AD symptoms?