4 ms·
That baffled me. They got a huge amount of stick for measuring up to the pre-determined cutoff point, which as I understand it is the correct way to do a scient
by makomk 6y ago
That baffled me. They got a huge amount of stick for measuring up to the pre-determined cutoff point, which as I understand it is the correct way to do a scientific study if you want your results to actually be valid...
- refurb 6y agoFrom what gathered, AZ said they had final data, but hadn’t actually finished the analysis, but preliminary numbers looked similar to interim so they just used those.
- mensetmanusman 6y agoThis. The reason it is risky to measure data after a predetermined stop point is that it lets human bias play a role in making conclusions. It is very subtle, but this human behavior has been a contributor to the replication crisis: https://en.m.wikipedia.org/wiki/Replication_crisis https://en.m.wikipedia.org/wiki/Replication_crisis