I use Dvorak on keyboards and qwerty on touch screens. I am pretty happy with both, but it doesn’t matter a lot regarding my eventual wrist or tendinitis pain.

I use Dvorak on keyboards and qwerty on touch screens. I am pretty happy with both, but it doesn’t matter a lot regarding my eventual wrist or tendinitis pain. What’s is important for me is drinking water sufficiently, regular exercise, a good posture, a good keyboard then finally the layout. I picked up Dvorak for no real reason 10 years ago; I kept up with it but would not really recommend it, specially because of its intense reliance on the right pinky. I don’t know much about Colemak.