Although they're different use cases, I'm not sure if virtualizing would be the right choice for performance issues; I've successfully run audio+MIDI software u

Although they're different use cases, I'm not sure if virtualizing would be the right choice for performance issues; I've successfully run audio+MIDI software under WINE using PlayOnLinux [0] which sort of [1] sandboxes each program into a virtual drive image therefore leaving untouched your ~/.wine directory, also allowing the use of different WINE versions for each program installed if needed. I also attempted to use virtualized Windows for MIDI software but the results were disappointing: although the software worked, it was unusable due to buffer underruns everywhere and huge latencies compared to either plain WINE or PlayOnLinux. 0: https://www.playonlinux.com/en/ https://www.playonlinux.com/en/ 1: It isolates the Windows program to a certain point, but I have no idea if it's technically a sandbox built for security which would protect the system against a Windows program willing to do any damage to or data exfiltration from the home directory.