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No. It is not meaningless. Had the vaccine had the same efficacy on the various variants, the ratio between them would have been the same. However it is not, in
by throwaway4good 6y ago
No. It is not meaningless. Had the vaccine had the same efficacy on the various variants, the ratio between them would have been the same. However it is not, indicating that the vaccine is vastly (factor of 8) more effective on the main variant compared to the SA / Brazil variants. Hence the conclusion.
It could do with more data but that has also been the case for similar studies of the AstraZenaca vaccine.
- Method-X 6y agoWouldn’t you need more than 800 people to get a statistically significant result?
- throwaway4good 6y agoThey check for significance in the paper. There is no magical sample size number. It depends on the size of the effect which here appears to be quite strong so a smaller sample would actually do.
- TeeMassive 6y agoThere's a factor of 8 because there are 8 variant cases. This is meaningless.