3 ms·

Are there any theories why this is happening? It it "just" the mentally difficult situation people are in, who get infected? Or is there some neurological dama

by andix 6y ago

Are there any theories why this is happening? It it "just" the mentally difficult situation people are in, who get infected? Or is there some neurological damage done by the virus? Maybe even permanent damage?

stult 6y ago
I am a bit suspicious of how this result is being presented in the media. The overwhelming bulk of the diagnoses are for anxiety and depression. Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic, and are fairly common reactions to long term recovery from a major illness even during less desperate times where treatment is more readily available. The elevated rates of stroke and dementia are more concerning, but are a less startling 7% and 2% respectively of the observed population. I’m not sure if the authors controlled well for confounding conditions either.
- enraged_camel 6y ago
  > Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic The article covers this: >> Anxiety, at 17%, and mood disorders, at 14%, were the most common, and did not appear to be related to how mild or severe the patient’s COVID-19 infection had been. So these disorders aren't caused by the trauma from hospitalization.
elif 6y ago
There is preliminary data on a condition being termed Multisystem Inflammatory Syndrome (MIS-C and MIS-A for adult and children versions), where there immune response to SARS-cov-2 causes any number of organs to become inflamed. However, very little is known about why it manifests or how extensive it is. Brain autoimmunity or even just cardiovascular restriction due to inflammation can cause neurological effects. * I am not a doctor, but had covid and have many of these symptoms
pilsetnieks 6y ago
One mechanism was discovered that could explain the brain fog, fatigue and other neuro symptoms - virus infiltration in bone marrow which leads to megakaryocyte cells (the cells that normally produce red blood cells) entering the bloodstream, settling in lungs, and getting trapped in small brain capillaries. https://www.hopkinsmedicine.org/news/newsroom/news-releases/covid-19-story-tip-researchers-may-have-unclouded-the-mystery-of-covid-19-brain-fog https://www.hopkinsmedicine.org/news/newsroom/news-releases/...

by andix 6y ago

stult 6y ago

I am a bit suspicious of how this result is being presented in the media. The overwhelming bulk of the diagnoses are for anxiety and depression. Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic, and are fairly common reactions to long term recovery from a major illness even during less desperate times where treatment is more readily available. The elevated rates of stroke and dementia are more concerning, but are a less startling 7% and 2% respectively of the observed population. I’m not sure if the authors controlled well for confounding conditions either.

enraged_camel 6y ago
> Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic The article covers this: >> Anxiety, at 17%, and mood disorders, at 14%, were the most common, and did not appear to be related to how mild or severe the patient’s COVID-19 infection had been. So these disorders aren't caused by the trauma from hospitalization.

elif 6y ago

There is preliminary data on a condition being termed Multisystem Inflammatory Syndrome (MIS-C and MIS-A for adult and children versions), where there immune response to SARS-cov-2 causes any number of organs to become inflamed. However, very little is known about why it manifests or how extensive it is. Brain autoimmunity or even just cardiovascular restriction due to inflammation can cause neurological effects. * I am not a doctor, but had covid and have many of these symptoms

pilsetnieks 6y ago

One mechanism was discovered that could explain the brain fog, fatigue and other neuro symptoms - virus infiltration in bone marrow which leads to megakaryocyte cells (the cells that normally produce red blood cells) entering the bloodstream, settling in lungs, and getting trapped in small brain capillaries. https://www.hopkinsmedicine.org/news/newsroom/news-releases/covid-19-story-tip-researchers-may-have-unclouded-the-mystery-of-covid-19-brain-fog https://www.hopkinsmedicine.org/news/newsroom/news-releases/...