6 ms·

A third of Covid survivors suffer neurological or mental disorders: study

44 points by unionpivo 6y ago

unionpivo 6y ago
This seems to be the study: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00084-5/fulltext https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0... Edit: Not sure maybe this should be the link ? But Reuters has nice synopsis
kreetx 6y ago
This was already discussed yesterday https://news.ycombinator.com/item?id=26730813 https://news.ycombinator.com/item?id=26730813
andix 6y ago
Are there any theories why this is happening? It it "just" the mentally difficult situation people are in, who get infected? Or is there some neurological damage done by the virus? Maybe even permanent damage?
- stult 6y ago
  I am a bit suspicious of how this result is being presented in the media. The overwhelming bulk of the diagnoses are for anxiety and depression. Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic, and are fairly common reactions to long term recovery from a major illness even during less desperate times where treatment is more readily available. The elevated rates of stroke and dementia are more concerning, but are a less startling 7% and 2% respectively of the observed population. I’m not sure if the authors controlled well for confounding conditions either.
  - enraged_camel 6y ago
    > Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic The article covers this: >> Anxiety, at 17%, and mood disorders, at 14%, were the most common, and did not appear to be related to how mild or severe the patient’s COVID-19 infection had been. So these disorders aren't caused by the trauma from hospitalization.
- elif 6y ago
  There is preliminary data on a condition being termed Multisystem Inflammatory Syndrome (MIS-C and MIS-A for adult and children versions), where there immune response to SARS-cov-2 causes any number of organs to become inflamed. However, very little is known about why it manifests or how extensive it is. Brain autoimmunity or even just cardiovascular restriction due to inflammation can cause neurological effects. * I am not a doctor, but had covid and have many of these symptoms
- pilsetnieks 6y ago
  One mechanism was discovered that could explain the brain fog, fatigue and other neuro symptoms - virus infiltration in bone marrow which leads to megakaryocyte cells (the cells that normally produce red blood cells) entering the bloodstream, settling in lungs, and getting trapped in small brain capillaries. https://www.hopkinsmedicine.org/news/newsroom/news-releases/covid-19-story-tip-researchers-may-have-unclouded-the-mystery-of-covid-19-brain-fog https://www.hopkinsmedicine.org/news/newsroom/news-releases/...
odshoifsdhfs 6y ago
Can the study result be: "A third of anyone suffer nerological or mental disorders due to the world situation/lockdowns'? My country just opened a couple things and I have been talking with a lot of friends/coaches/workers. Pretty much every one of them (including myself) have these symptoms, having caught covid or not. I see people that were in general 'happy' feel depressed, run down, see little hope. I see their 'face' changes from pre covid to post covid. The people that lost their jobs. Not wanting to be pro/against lockdowns, but I believe we will see a long effects of this for years to come.
- newacct583 6y ago
  > Can the study result be: "A third of anyone suffer nerological or mental disorders due to the world situation/lockdowns'? No, because basic science says you control for stuff like that (no, I didn't read the full study) when computing your result. Lockdowns may be difficult, and that's worth studying too. But they were clearly needed, and evidence like this is why. Covid is really bad.
- hef19898 6y ago
  Or it is due to general uncertainty, anxiety due to the on going pandemic, having lost someone... Countless of reasons. So the article took a subset, Covid survivors. If it is a general problem, and if so why, can only be answered by additional studies. A conclusive answer might be difficult to get so.
- phreeza 6y ago
  Please take a look at the study before making such an offhand comment. It clearly shows that these effects are more likely for people who actually got COVID than for the control cohort, who experienced the same lockdown measures, by a factor of 80%. https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/c1226b99-84f4-4dbf-b42a-8195017c3226/gr1_lrg.jpg https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachme...
  - jMyles 6y ago
    People who got covid19 during a lockdown were also more likely to be in harrowing situations: working 'essential' jobs, living in multigen households in constant fear of infecting loved ones, etc. I don't think that this is an effective control. Of course people who got the virus are during the lockdown are even more likely to have traumatic effects from the lockdown. I'm surprised it's only 80%.
totalminimalist 6y ago
Something that has been proven to work in severely lowering your chances of ever getting it (vax not taken into consideration) is taking a combination of green tea extract and a zinc/quercetin. Many research teams have proven this combo to kill covid dead. We take this daily. https://www.mcgilltribune.com/sci-tech/montreal-researchers-propose-a-treatment-for-covid-19-170320/ https://www.mcgilltribune.com/sci-tech/montreal-researchers-... Editing to say that I am not opposed to the vaccine, but cannot yet get it here in Texas. Taking this combo does reduce risk. Something is better than nothing.

44 points by unionpivo 6y ago

This seems to be the study: https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00084-5/fulltext https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0... Edit: Not sure maybe this should be the link ? But Reuters has nice synopsis

kreetx 6y ago

This was already discussed yesterday https://news.ycombinator.com/item?id=26730813 https://news.ycombinator.com/item?id=26730813

andix 6y ago

Are there any theories why this is happening? It it "just" the mentally difficult situation people are in, who get infected? Or is there some neurological damage done by the virus? Maybe even permanent damage?

stult 6y ago
I am a bit suspicious of how this result is being presented in the media. The overwhelming bulk of the diagnoses are for anxiety and depression. Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic, and are fairly common reactions to long term recovery from a major illness even during less desperate times where treatment is more readily available. The elevated rates of stroke and dementia are more concerning, but are a less startling 7% and 2% respectively of the observed population. I’m not sure if the authors controlled well for confounding conditions either.
- enraged_camel 6y ago
  > Which seem like pretty typical reactions to an extreme emotional trauma like hospitalization during a pandemic The article covers this: >> Anxiety, at 17%, and mood disorders, at 14%, were the most common, and did not appear to be related to how mild or severe the patient’s COVID-19 infection had been. So these disorders aren't caused by the trauma from hospitalization.
elif 6y ago
There is preliminary data on a condition being termed Multisystem Inflammatory Syndrome (MIS-C and MIS-A for adult and children versions), where there immune response to SARS-cov-2 causes any number of organs to become inflamed. However, very little is known about why it manifests or how extensive it is. Brain autoimmunity or even just cardiovascular restriction due to inflammation can cause neurological effects. * I am not a doctor, but had covid and have many of these symptoms
pilsetnieks 6y ago
One mechanism was discovered that could explain the brain fog, fatigue and other neuro symptoms - virus infiltration in bone marrow which leads to megakaryocyte cells (the cells that normally produce red blood cells) entering the bloodstream, settling in lungs, and getting trapped in small brain capillaries. https://www.hopkinsmedicine.org/news/newsroom/news-releases/covid-19-story-tip-researchers-may-have-unclouded-the-mystery-of-covid-19-brain-fog https://www.hopkinsmedicine.org/news/newsroom/news-releases/...

odshoifsdhfs 6y ago

Can the study result be: "A third of anyone suffer nerological or mental disorders due to the world situation/lockdowns'? My country just opened a couple things and I have been talking with a lot of friends/coaches/workers. Pretty much every one of them (including myself) have these symptoms, having caught covid or not. I see people that were in general 'happy' feel depressed, run down, see little hope. I see their 'face' changes from pre covid to post covid. The people that lost their jobs. Not wanting to be pro/against lockdowns, but I believe we will see a long effects of this for years to come.

newacct583 6y ago
> Can the study result be: "A third of anyone suffer nerological or mental disorders due to the world situation/lockdowns'? No, because basic science says you control for stuff like that (no, I didn't read the full study) when computing your result. Lockdowns may be difficult, and that's worth studying too. But they were clearly needed, and evidence like this is why. Covid is really bad.
hef19898 6y ago
Or it is due to general uncertainty, anxiety due to the on going pandemic, having lost someone... Countless of reasons. So the article took a subset, Covid survivors. If it is a general problem, and if so why, can only be answered by additional studies. A conclusive answer might be difficult to get so.
phreeza 6y ago
Please take a look at the study before making such an offhand comment. It clearly shows that these effects are more likely for people who actually got COVID than for the control cohort, who experienced the same lockdown measures, by a factor of 80%. https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/c1226b99-84f4-4dbf-b42a-8195017c3226/gr1_lrg.jpg https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachme...
- jMyles 6y ago
  People who got covid19 during a lockdown were also more likely to be in harrowing situations: working 'essential' jobs, living in multigen households in constant fear of infecting loved ones, etc. I don't think that this is an effective control. Of course people who got the virus are during the lockdown are even more likely to have traumatic effects from the lockdown. I'm surprised it's only 80%.

totalminimalist 6y ago

Something that has been proven to work in severely lowering your chances of ever getting it (vax not taken into consideration) is taking a combination of green tea extract and a zinc/quercetin. Many research teams have proven this combo to kill covid dead. We take this daily. https://www.mcgilltribune.com/sci-tech/montreal-researchers-propose-a-treatment-for-covid-19-170320/ https://www.mcgilltribune.com/sci-tech/montreal-researchers-... Editing to say that I am not opposed to the vaccine, but cannot yet get it here in Texas. Taking this combo does reduce risk. Something is better than nothing.