3 ms·
I was incorrect in saying that stimulants are SNRIS, they are NDRIs as you say, however my point still stands. I don't understand the difference between e.g Add
by The_rationalist 6y ago
I was incorrect in saying that stimulants are SNRIS, they are NDRIs as you say, however my point still stands.
I don't understand the difference between e.g Adderall and Wellbutrin (which is an NDRI antidepressant)
Amphetamine is a releasing agent too good point but this additional aspect aside, dextroamphetamine should have the same antidepressant effect as Wellbutrin and I don't think that is the case, for an unknown reason.
Different drugs have different receptor affinities.
Oh I thought Adderall was non-selective (affecting all receptors) but I might be wrong and that would be a possible explanation!
And the different metabolites do too. I don't know what this can imply.
- pseudalopex 6y agoDextroamphetamine was prescribed for depression before other classes of drugs were invented. And bupropion is prescribed off label for ADHD. Amphetamine has much stronger dopaminergic effects though. No 2 drugs are exactly alike. Their different metabolites also have their own effects.