We serve one of the largest sites on the internet (top 2,000 last time that alexa's top sites worked, 25k requests per minute) with Django and a tiny web server

We serve one of the largest sites on the internet (top 2,000 last time that alexa's top sites worked, 25k requests per minute) with Django and a tiny web server budget (~$1k/mo). We serve mostly static files, but all requests hit Django at least 2-3 times. If it works for us, it will work for you :)