3 ms·
My understanding is that many HIV vaccine candidates have showed promising Phase I results but so far they have all failed in later trials. https://en.wikipedi
by argonaut 6y ago
My understanding is that many HIV vaccine candidates have showed promising Phase I results but so far they have all failed in later trials.
https://en.wikipedia.org/wiki/HIV_vaccine_development https://en.wikipedia.org/wiki/HIV_vaccine_development lists five vaccines that made it to Phase 2-3 (and all failed). Two of them appeared to increase the risk of contracting HIV. The strongest candidate appears to have been ~30% effective.
- djmips 6y agoInteresting that there was some warnings given about using the same vectored technique on a Covid vaccine (AstraZeneca is an example) could also potentially increase the risk of contracting HIV? https://www.ajmc.com/view/researchers-warn-of-heightened-risk-of-hiv-with-certain-covid-19-vaccines https://www.ajmc.com/view/researchers-warn-of-heightened-ris... Note that Johnson & Johnson and AstraZeneca use different adenoviruses as vectors than Merck’s failed Ad5 vaccine.