>Right but for a virus that integrates into the genome once it takes hold it's game over. The same could be said about any other successful vaccine, like Polio

>Right but for a virus that integrates into the genome once it takes hold it's game over. The same could be said about any other successful vaccine, like Polio and Measles vaccines. Not that those diseases behave like HIV, but the way we handle vaccination against them. >And even vaccine mediated immune responses are via memory cells and take time to ramp up to generate the antibodies to attack the virus. That's why there are vaccination campaigns, to immunize target groups before they contract the aforementioned sickness. >Is the window of opportunity while ramping up the immune system for a vaccine I mean unresponse big enough for HIV to take root in a body. A vaccine is always a good opportunity to prevent adverse effects, even "if takes time" to ramp up your immune system.