4 ms·
Moderna and Pfizer seem to be nearly bit-for-bit identical at the mRNA level, though Moderna seems to have stabilized the mRNA better to be viable at higher tem
by wycy 6y ago
Moderna and Pfizer seem to be nearly bit-for-bit identical at the mRNA level, though Moderna seems to have stabilized the mRNA better to be viable at higher temperatures.
J&J appears to be slightly less effective with its one dose, but would probably be just as effective as Moderna and Pfizer (if not more) if a second dose were given. J&J simply doesn't need the second dose because 75+% is still considered extremely good.
Even though J&J isn't considered one of the "mRNA vaccines", it still functions similarly to the mRNA vaccines. Their adenovirus carries the mRNA, allowing it to be remain stable in your body for longer, building strong immunity from 1 dose.
- solosoyokaze 6y agoA single dose of Moderna or Pfizer is 80% effective: https://www.cnbc.com/2021/03/29/cdc-study-shows-single-dose-of-pfizer-or-moderna-covid-vaccines-was-80percent-effective.html https://www.cnbc.com/2021/03/29/cdc-study-shows-single-dose-...
- wycy 6y agoThis appears to be a very new finding. I seem to remember earlier studies suggesting single doses of Moderna/Pfizer were between ~53-70% effective. The number 53 sticks out in my memory for some reason. Could be misremembering though. Edit: Looks like the earlier results I was thinking of say 52% effectiveness from 1 dose, but that included people who were infected very shortly after the first dose. > Using the data from the published study of the Pfizer vaccine, Public Health England determined that vaccine efficacy was 89% for 15-21 days after dose 1 – and before dose 2 on day 21. The range was between 52% and 97%. Source: https://globalbiodefense.com/2021/03/20/how-effective-is-the-first-shot-of-the-pfizer-or-moderna-vaccine/ https://globalbiodefense.com/2021/03/20/how-effective-is-the...