If the airplane is slightly out of trim, yes, but it is tiring. If it is grossly out of trim, then it may require full effort with both arms. Similarly, if the

If the airplane is slightly out of trim, yes, but it is tiring. If it is grossly out of trim, then it may require full effort with both arms. Similarly, if the airplane is slightly out of trim, manual trim adjustment is no big deal and does not require a lot of force or attention. If the airplane is grossly out of trim, the air loads can prevent manual movement of the trim wheel. Boeing previously provided guidance in the Quick Reference Handbook to briefly relax elevator control inputs while adjusting trim if this occurs, but that guidance was apparently removed many years ago. Was colloquially referred to as the roller-coaster maneuver, sounds like great fun for the folks in back.