Amphetamine and methamphetamine are actually approved as treatments for morbid obesity by the FDA in America. AMP is actually still used in some cases today, t

Amphetamine and methamphetamine are actually approved as treatments for morbid obesity by the FDA in America. AMP is actually still used in some cases today, though much more sparingly than historically. The side-effects and potential dependency make their use often very problematic. Still, between increasing the base metabolic rate and energy levels, and suppressing appetite, they do work. While caffeine has a very different mechanism of action, it does appear to indirectly work on the same dopamine-adenosine system. So it's not too surprising it'd work much the same way for weight loss. And fortunately caffeine seems to be mostly self-limiting in its compulsiveness.