Of course, to perform any valid statistical reasoning, you need to consider the prior. The standard model has held up very well, and we do a lot of experiments

Of course, to perform any valid statistical reasoning, you need to consider the prior. The standard model has held up very well, and we do a lot of experiments-- any of which has a small chance of popping out a result that looks highly significant by chance. There's a reason why 6 sigma is the line to take things super seriously (in fundamental physics).