4 ms·
In addition to everything else mentioned, the UK is also prioritizing first-doses while delaying the second dose far later than recommended (second dose at 12 w
by chimeracoder 6y ago
In addition to everything else mentioned, the UK is also prioritizing first-doses while delaying the second dose far later than recommended (second dose at 12 weeks, instead of 3-4 weeks)[0]. That's on top of administering first doses without keeping a complete stockpile for second doses (ie, they are betting that it will be relatively easy to obtain a supply of second doses when the time comes).
So yes, the UK is far ahead of most other countries in first doses administered, but they're also going off-book for their vaccination protocol in a lot of ways that make it a bad point of comparison for other countries which are following clinical recommendations more closely.
[0] There's some clinical evidence in support of the 12-week gap for the AstraZeneca vaccine, though the UK made this decision before that study had been released, and there is not yet analogous data to support the efficacy of a 12-week period for the Pfizer and Moderna vaccines, which the UK is also administering on a 12-week gap.
- orangecat 6y agoBoth theory and data overwhelmingly support delaying second doses in favor of getting first doses to more people, e.g. https://marginalrevolution.com/marginalrevolution/2021/02/first-doses-first-the-data-is-arriving.html https://marginalrevolution.com/marginalrevolution/2021/02/fi.... Notably, the "recommended" 3 week delay wasn't the result of determining the medically optimal interval; it was chosen to reduce the time needed for vaccine trials.
- mprovost 6y agoThe UK has been vaccinating for more than 12 weeks now and the evidence shows that people aren't getting infected in that time period once they've had their first dose.