4 ms·
This is not well aligned with other research[1] showing the Pfizer and Moderna vaccines perform little better against the B1351 (South Africa) variant than they
by spchampion2 6y ago
This is not well aligned with other research[1] showing the Pfizer and Moderna vaccines perform little better against the B1351 (South Africa) variant than they do against plain old SARS and distantly related bat COVIDs. They're also only semi-effective against the Brazilian P1 variant.
Right now, all of the vaccines are reasonably effective against the variants commonly circulating in the US (including B117), which is what the JAMA article tested. But I worry for how well they'll perform in a few months when the other variants get a foothold.
[1]: https://www.cell.com/cell/pdf/S0092-8674(21)00298-1.pdf https://www.cell.com/cell/pdf/S0092-8674(21)00298-1.pdf
- anonuser123456 6y agoThe article is talking about "escape neutralization". Neutralizing antibodies are not the only mechanism of the immune system, and the article even discusses another such mechanism: T cell immunity. T cell immunity appears robust for all variants from the data I've seen.
- spchampion2 6y agoAs far as I can tell, both the JAMA study linked in this post and the study I linked are describing antibody responses. I was trying to make an apples-to-apples comparison by sharing a similar study with contradictory results on a broader swath of virus variants.