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I was wondering the same thing. Vaccination means exercising against a mockup foe before meeting the real enemy. But the cancer patient is already deep into the
by usrusr 6y ago
I was wondering the same thing. Vaccination means exercising against a mockup foe before meeting the real enemy. But the cancer patient is already deep into the battle, how could adding mockup enemies help winning?
Perhaps the molecules they want the immune system to attack aren't sufficiently mobile, sticking to the tumor instead of diffusing into the entire body?
From what I've picked up in the pandemic the immune system has a dedicated proving ground spots where experimentation is happening, and relies on special cells to transport foe candidates into those proving grounds (just like a programmer would gather problematic input samples in their unit tests). Maybe the tumor bits they want attacked cannot be transported to "lab organ", but fragments created separately, from mRNA injections, could, and once the immune system is producing antibodies against those fragments they will also react with the immobile real tumor bits.
Purely speculative on my part, but maybe it really is something along those lines?
- samus 6y agoThe core issue with cancer is that the immune system does not combat the tumor. Cancer patients suffer from damage caused by the tumor and by aggressive therapies. Cancerous mutations happen all the time. Usually, the affected cells either * repair the damage, * get wrecked by the damage's side effects, * suicide or * get blasted by the immune system because the mutation alters their surface proteins in weird ways. Tumors form because the cancerous mutations succeed to fly under the radar of the immune system. mRNA therapy can be used to make the immune system target specific surface features of cancer cells, or to do something else in connection with the cancer cells that attracts the immune system's attention.